American Society for Reproductive Medicine (ASRM) Guidelines for Elective Single Embryo (eSET)

American Society for Reproductive Medicine (ASRM) Guidelines for Elective Single Embryo (eSET) are that you should council every patient who is a good prognosis patient under the age of 38.

Ideally the transfers for Elective Single Embryo are executed on day 3 and day 5 embryo transfers:

  • One to two embryos should be inserted on day 3 embryos
  • One embryo should be inserted on day 5 blastocyst

Elective Single Embryo (eSET) versus Dual Embryo Transfer

The difference is the transfer of one versus two embryos. The problem with transferring two embryos is you still carry a very high twin rate, especially true with day 5 embryos.

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Embryo Transfers
Day 3 vs Day 5 Blastocyst Transfers: There are very different schools of thought as to whether to perform a Day 3 or Day 5 Blastocyst stage embryo transfer. Not all Day 2 or 3 embryos can develop to a blastocyst with a loss of about 45 – 60% of your embryos as they are cultured the extra 2 or 3 days.